Vol. 1 (2026): EFFECTIVENESS OF NURSING INTERVENTIONS FOR END-STAGE KIDNEY DISEASE (ESKD) IN INDONESIA: SYSTEMATIC REVIEW 2020-2025
The escalating burden of End-Stage Kidney Disease (ESKD) in Indonesia necessitates
evidence-based strategies to improve patient outcomes. Nurses play a pivotal role through
structured interventions, yet a comprehensive synthesis of their effectiveness within the unique
Indonesian context is lacking. This systematic review aimed to synthesize evidence on the
effectiveness of nursing interventions for ESKD patients in Indonesia from 2020 to
2025. Following PRISMA guidelines, a systematic search was conducted across PubMed,
CINAHL, Scopus, Web of Science, and SINTA databases. Experimental and quasi
experimental studies evaluating nursing interventions for Indonesian ESKD adults were
included. Study selection, data extraction, and quality assessment using standardized tools were
performed independently by two reviewers. Fifteen studies (n=987 participants) were included.
Interventions were categorized into educational/self-management (n=9), psychoeducational
(n=4), and technology-based (n=2). Educational interventions consistently demonstrated
significant reductions in interdialytic weight gain and improved adherence behaviors.
Psychoeducational support effectively reduced symptoms of depression and anxiety and
enhanced quality of life domains. Technology-based interventions showed promise for self
efficacy but had limited evidence. Major contextual barriers included time constraints in
hemodialysis units. A significant gap was identified in community-based and peritoneal dialysis
studies. Nursing interventions, particularly structured education and psychosocial support, are
effective in improving key clinical and patient-reported outcomes for ESKD patients in
Indonesia. Future research should address implementation barriers, explore cost-effectiveness,
and expand to underserved settings and non-hemodialysis populations to strengthen equitable,
evidence-based nephrology nursing practice nationwide.
Published: 2026-02-02